ITGB1 Antikörper
Kurzübersicht für ITGB1 Antikörper (ABIN1106227)
Target
Alle ITGB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Aufreinigung
- Protein A agarose
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Immunogen
- G-361 human melanoma cell line
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Prepare a stock solution by dissolving the lyophilized antibody in 100 μL of distilled water. After reconstitution, the IgG concentration should be 1 mg/mL.
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Buffer
- PBS ( pH 7.2), 1 % sucrose
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.
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- ITGB1 (Integrin beta 1 (ITGB1))
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Andere Bezeichnung
- CD29 / Integrin beta-1
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Hintergrund
- The integrin family of adhesion molecules participate in important cell-cell and cell-extracellular matrix interactions in a diverse range of biological processes. Integrins are heterodimers consisting of an a subunit and a ß subunit. Both a and ß subunits are transmembrane proteins with large extracellular domains (>100 kDa for a subunit and >75 kDa for ß subunit) that interact with extracellular matrix proteins and relatively small cytoplasmic domains (50 amino acids or less, except for the ß4 subunit) that interact with cytoskeletal proteins. The adhesiveness of integrins is dynamically regulated in response to cytoplasmic signals, termed Synonyms: FNRB, Fibronectin receptor subunit beta, ITGB1, Integrin VLA-4 subunit beta, MDF2, MSK12
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Gen-ID
- 9606
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UniProt
- P05556
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Pathways
- Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interaktom
Target
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